Explanation:

Microsoft Entra Conditional Access evaluates signals to make real-time access decisions. Microsoft describes it as bringing "signals together to make decisions and enforce organizational policies," where administrators choose controls such as Block access, Require multi-factor authentication, Require device to be marked as compliant, or Require hybrid Azure AD joined device. Because MFA is only one of several grant controls, it is incorrect that policies always enforce MFA; they can also simply block, allow, or require other conditions.
Location is a first-class condition. Microsoft states you can define named locations (by countries/regions or IP ranges) and then use them in policy conditions to block or grant access. A common scenario is "Block access from specific locations" or require additional controls when a sign-in originates from an untrusted network.
Therefore, Conditional Access can block access to an application based on user location.
Finally, Conditional Access targets users, groups, workload identities, and cloud apps regardless of device join state. Device-related conditions and filters are optional; policies are not limited to "Azure AD-joined devices." Controls like Require device to be marked as compliant or Require Hybrid Azure AD joined device are only enforced if configured. Hence, Conditional Access does not only affect users on Azure AD-joined devices.